TnSeqCorr

• These are correlations of TnSeq responses across 82 experimental conditions.
• LFCs (log2-fold-changes) were computed for each gene in each condition relative to a relevant control condition (e.g. H37Rv grown on 7H9).
• The LFCs were normalized by dividing by the standard deviation for each condition. (so roughly, |LFC|>2 are the outliers, i.e. tails of the distribution)
• Note that essential genes often have LFCs around 0.
• Data for some genes is not available if they have less than 3 TA sites, or the dynamic range of LFCs is less than 2.0 across all conditions. (This is the case for many essential genes.)
• 'leverage' on each plot is a statistical score that indicates how much the regression is influenced by a few outlier points; the traditional threshold is indicated on the plots (3p/n, which is about 0.07 for this dataset), but in practice, cases with leverage > ~0.2 seem to be the least reliable (most misleading) correlation coefficients.

Top 10 genes with highest correlation to Rv3909/-:
none

Correlation of Rv3909/- with Rv3909/-

Normalized LFCs for Rv3909/-:
(description and provenance of datasets)

	Rv3909/-	Rv3909/-
Fe_supp_jason_reseq	0.0	0.0
low_pH_jason_reseq	0.0	0.0
NO_jason_reseq	0.0	0.0
B6_jason_reseq	0.0	0.0
MHCII_jason_reseq	0.0	0.0
Isoniazid02	0.201	0.201
Rifampicin4	0.374	0.374
Ethambutol3	0.168	0.168
Meropenem3	0.315	0.315
Vancomycin16	0.366	0.366
Rv2680_day32	-0.063	-0.063
H37Rv_KO_MarP	-0.371	-0.371
hypoxia_3wks	0.0	0.0
hypoxia_6wks	0.288	0.288
glycerol	0.0	0.0
cholesterol	0.0	0.0
AJ	0.0	0.0
Bibs02	0.0	0.0
Bibs02c	0.0	0.0
BL6	0.768	0.768
BL6a	0.0	0.0
BXD01	0.0	0.0
BXD010	0.543	0.543
BXD011	0.0	0.0
BXD03	0.573	0.573
BXD04	0.0	0.0
BXD05	0.747	0.747
BXD06	0.0	0.0
BXD07	0.0	0.0
BXD08	0.0	0.0
BXD09	0.0	0.0
CAST	0.0	0.0
CCcont	0.149	0.149
DS01	0.0	0.0
DS02	0.0	0.0
DS04	0.0	0.0
DS0c	0.0	0.0
GP01	0.0	0.0
GP02	0.0	0.0
GP0c	0.248	0.248
NOD	0.0	0.0
NZO	0.0	0.0
PWK	0.0	0.0
H37Rv_KO_CtpC	0.0	0.0
H37Rv_KO_CtpD	0.0	0.0
H37Rv_KO_Rv1272	0.0	0.0
H37Rv_KO_SugABC	0.0	0.0
H37Rv_KO_MbtN	0.0	0.0
Trans05	0.0	0.0
macrophage_unactivated	0.761	0.761
IL1	0.374	0.374
Rapamycin	0.0	0.0
Tcell	0.785	0.785
GMCSF	-0.364	-0.364
IFNab	0.381	0.381
IFNg	0.337	0.337
IFNg_GMCSF1	0.0	0.0
Rv1432_day32	-0.494	-0.494
Rv1565c_day32	0.0	0.0
secA2_input	-0.759	-0.759
delta_Rv3594	0.742	0.742
delta_Rv3717	0.964	0.964
delta_Rv3811	0.87	0.87
delta_Rv0954	0.0	0.0
PonA1	0.56	0.56
EccD1_KO	-0.865	-0.865
EspI_KO	-0.359	-0.359
PE35_KO	-0.368	-0.368
PPE68_KO	-0.403	-0.403
glycerol2	0.0	0.0
lignocerate	0.0	0.0
oleate	0.0	0.0
phosphatidylcholine	0.0	0.0
acetate	0.0	0.0
glucAc	0.143	0.143
Rv0950ko	0.0	0.0
Rv1096ko	0.416	0.416
Rv3684ko	0.452	0.452
delta_otsA_trehalose	0.0	0.0