TnSeqCorr

• These are correlations of TnSeq responses across 82 experimental conditions.
• LFCs (log2-fold-changes) were computed for each gene in each condition relative to a relevant control condition (e.g. H37Rv grown on 7H9).
• The LFCs were normalized by dividing by the standard deviation for each condition. (so roughly, |LFC|>2 are the outliers, i.e. tails of the distribution)
• Note that essential genes often have LFCs around 0.
• Data for some genes is not available if they have less than 3 TA sites, or the dynamic range of LFCs is less than 2.0 across all conditions. (This is the case for many essential genes.)
• 'leverage' on each plot is a statistical score that indicates how much the regression is influenced by a few outlier points; the traditional threshold is indicated on the plots (3p/n, which is about 0.07 for this dataset), but in practice, cases with leverage > ~0.2 seem to be the least reliable (most misleading) correlation coefficients.

Top 10 genes with highest correlation to Rv3503c/fdxD:
none

Correlation of Rv3503c/fdxD with Rv3503c/fdxD

Normalized LFCs for Rv3503c/fdxD:
(description and provenance of datasets)

	Rv3503c/fdxD	Rv3503c/fdxD
Fe_supp_jason_reseq	-0.125	-0.125
low_pH_jason_reseq	0.064	0.064
NO_jason_reseq	1.202	1.202
B6_jason_reseq	0.019	0.019
MHCII_jason_reseq	1.018	1.018
Isoniazid02	-1.161	-1.161
Rifampicin4	0.122	0.122
Ethambutol3	-0.97	-0.97
Meropenem3	0.317	0.317
Vancomycin16	-0.302	-0.302
Rv2680_day32	-1.185	-1.185
H37Rv_KO_MarP	0.346	0.346
hypoxia_3wks	0.199	0.199
hypoxia_6wks	-0.393	-0.393
glycerol	-2.245	-2.245
cholesterol	-5.762	-5.762
AJ	-2.16	-2.16
Bibs02	-1.45	-1.45
Bibs02c	-2.511	-2.511
BL6	0.327	0.327
BL6a	-1.022	-1.022
BXD01	0.731	0.731
BXD010	-0.585	-0.585
BXD011	-0.494	-0.494
BXD03	-0.21	-0.21
BXD04	1.266	1.266
BXD05	-0.488	-0.488
BXD06	-0.484	-0.484
BXD07	0.413	0.413
BXD08	0.31	0.31
BXD09	-0.282	-0.282
CAST	-1.428	-1.428
CCcont	-0.585	-0.585
DS01	-2.637	-2.637
DS02	-0.952	-0.952
DS04	-2.932	-2.932
DS0c	-1.054	-1.054
GP01	-2.091	-2.091
GP02	-1.714	-1.714
GP0c	-1.439	-1.439
NOD	-2.428	-2.428
NZO	-0.912	-0.912
PWK	-1.901	-1.901
H37Rv_KO_CtpC	-4.453	-4.453
H37Rv_KO_CtpD	-2.555	-2.555
H37Rv_KO_Rv1272	0.993	0.993
H37Rv_KO_SugABC	-2.875	-2.875
H37Rv_KO_MbtN	-1.531	-1.531
Trans05	-0.184	-0.184
macrophage_unactivated	0.688	0.688
IL1	2.406	2.406
Rapamycin	1.973	1.973
Tcell	0.098	0.098
GMCSF	-0.615	-0.615
IFNab	-0.529	-0.529
IFNg	-0.484	-0.484
IFNg_GMCSF1	-0.201	-0.201
Rv1432_day32	-2.422	-2.422
Rv1565c_day32	0.194	0.194
secA2_input	-2.177	-2.177
delta_Rv3594	-0.271	-0.271
delta_Rv3717	-0.43	-0.43
delta_Rv3811	-0.36	-0.36
delta_Rv0954	-0.788	-0.788
PonA1	-0.585	-0.585
EccD1_KO	0.332	0.332
EspI_KO	0.57	0.57
PE35_KO	-0.893	-0.893
PPE68_KO	-0.666	-0.666
glycerol2	0.621	0.621
lignocerate	0.492	0.492
oleate	0.832	0.832
phosphatidylcholine	0.749	0.749
acetate	-0.703	-0.703
glucAc	-0.636	-0.636
Rv0950ko	0.944	0.944
Rv1096ko	0.0	0.0
Rv3684ko	0.498	0.498
delta_otsA_trehalose	0.197	0.197