TnSeqCorr

• These are correlations of TnSeq responses across 82 experimental conditions.
• LFCs (log2-fold-changes) were computed for each gene in each condition relative to a relevant control condition (e.g. H37Rv grown on 7H9).
• The LFCs were normalized by dividing by the standard deviation for each condition. (so roughly, |LFC|>2 are the outliers, i.e. tails of the distribution)
• Note that essential genes often have LFCs around 0.
• Data for some genes is not available if they have less than 3 TA sites, or the dynamic range of LFCs is less than 2.0 across all conditions. (This is the case for many essential genes.)
• 'leverage' on each plot is a statistical score that indicates how much the regression is influenced by a few outlier points; the traditional threshold is indicated on the plots (3p/n, which is about 0.07 for this dataset), but in practice, cases with leverage > ~0.2 seem to be the least reliable (most misleading) correlation coefficients.

Top 10 genes with highest correlation to Rv3402c/-:
none

Correlation of Rv3402c/- with Rv3402c/-

Normalized LFCs for Rv3402c/-:
(description and provenance of datasets)

	Rv3402c/-	Rv3402c/-
Fe_supp_jason_reseq	0.204	0.204
low_pH_jason_reseq	-0.259	-0.259
NO_jason_reseq	-0.407	-0.407
B6_jason_reseq	-0.403	-0.403
MHCII_jason_reseq	0.247	0.247
Isoniazid02	0.252	0.252
Rifampicin4	-0.195	-0.195
Ethambutol3	-0.055	-0.055
Meropenem3	0.758	0.758
Vancomycin16	0.101	0.101
Rv2680_day32	0.577	0.577
H37Rv_KO_MarP	0.248	0.248
hypoxia_3wks	0.0	0.0
hypoxia_6wks	-0.407	-0.407
glycerol	0.462	0.462
cholesterol	-0.052	-0.052
AJ	-0.225	-0.225
Bibs02	0.119	0.119
Bibs02c	0.253	0.253
BL6	0.911	0.911
BL6a	-0.116	-0.116
BXD01	-0.237	-0.237
BXD010	0.576	0.576
BXD011	0.494	0.494
BXD03	-0.015	-0.015
BXD04	0.093	0.093
BXD05	0.281	0.281
BXD06	-0.034	-0.034
BXD07	0.019	0.019
BXD08	-0.129	-0.129
BXD09	0.092	0.092
CAST	0.264	0.264
CCcont	-0.265	-0.265
DS01	0.147	0.147
DS02	-0.11	-0.11
DS04	0.153	0.153
DS0c	0.228	0.228
GP01	0.56	0.56
GP02	0.54	0.54
GP0c	-0.061	-0.061
NOD	0.43	0.43
NZO	-0.155	-0.155
PWK	0.504	0.504
H37Rv_KO_CtpC	-0.741	-0.741
H37Rv_KO_CtpD	0.364	0.364
H37Rv_KO_Rv1272	-0.495	-0.495
H37Rv_KO_SugABC	0.032	0.032
H37Rv_KO_MbtN	0.379	0.379
Trans05	-0.21	-0.21
macrophage_unactivated	0.051	0.051
IL1	-0.338	-0.338
Rapamycin	0.218	0.218
Tcell	-0.209	-0.209
GMCSF	0.227	0.227
IFNab	0.124	0.124
IFNg	0.371	0.371
IFNg_GMCSF1	0.751	0.751
Rv1432_day32	0.617	0.617
Rv1565c_day32	0.134	0.134
secA2_input	0.401	0.401
delta_Rv3594	-0.561	-0.561
delta_Rv3717	-0.614	-0.614
delta_Rv3811	-0.396	-0.396
delta_Rv0954	-0.419	-0.419
PonA1	-0.459	-0.459
EccD1_KO	0.49	0.49
EspI_KO	-0.436	-0.436
PE35_KO	0.05	0.05
PPE68_KO	-0.288	-0.288
glycerol2	0.07	0.07
lignocerate	0.142	0.142
oleate	0.403	0.403
phosphatidylcholine	0.196	0.196
acetate	-0.053	-0.053
glucAc	-0.252	-0.252
Rv0950ko	0.585	0.585
Rv1096ko	0.618	0.618
Rv3684ko	0.102	0.102
delta_otsA_trehalose	0.329	0.329