TnSeqCorr

• These are correlations of TnSeq responses across 82 experimental conditions.
• LFCs (log2-fold-changes) were computed for each gene in each condition relative to a relevant control condition (e.g. H37Rv grown on 7H9).
• The LFCs were normalized by dividing by the standard deviation for each condition. (so roughly, |LFC|>2 are the outliers, i.e. tails of the distribution)
• Note that essential genes often have LFCs around 0.
• Data for some genes is not available if they have less than 3 TA sites, or the dynamic range of LFCs is less than 2.0 across all conditions. (This is the case for many essential genes.)
• 'leverage' on each plot is a statistical score that indicates how much the regression is influenced by a few outlier points; the traditional threshold is indicated on the plots (3p/n, which is about 0.07 for this dataset), but in practice, cases with leverage > ~0.2 seem to be the least reliable (most misleading) correlation coefficients.

Top 10 genes with highest correlation to Rv2588c/yajC:
none

Correlation of Rv2588c/yajC with Rv2588c/yajC

Normalized LFCs for Rv2588c/yajC:
(description and provenance of datasets)

	Rv2588c/yajC	Rv2588c/yajC
Fe_supp_jason_reseq	-0.818	-0.818
low_pH_jason_reseq	-1.004	-1.004
NO_jason_reseq	-0.013	-0.013
B6_jason_reseq	-0.998	-0.998
MHCII_jason_reseq	0.173	0.173
Isoniazid02	-0.141	-0.141
Rifampicin4	1.362	1.362
Ethambutol3	-1.503	-1.503
Meropenem3	0.64	0.64
Vancomycin16	1.464	1.464
Rv2680_day32	1.178	1.178
H37Rv_KO_MarP	-2.309	-2.309
hypoxia_3wks	0.088	0.088
hypoxia_6wks	0.39	0.39
glycerol	-1.966	-1.966
cholesterol	0.287	0.287
AJ	0.405	0.405
Bibs02	-0.836	-0.836
Bibs02c	-0.767	-0.767
BL6	-0.648	-0.648
BL6a	-0.816	-0.816
BXD01	-0.918	-0.918
BXD010	-0.282	-0.282
BXD011	0.134	0.134
BXD03	-0.554	-0.554
BXD04	-0.413	-0.413
BXD05	-0.612	-0.612
BXD06	-0.489	-0.489
BXD07	-1.269	-1.269
BXD08	-0.516	-0.516
BXD09	-0.525	-0.525
CAST	0.015	0.015
CCcont	-1.067	-1.067
DS01	-0.515	-0.515
DS02	-0.011	-0.011
DS04	0.54	0.54
DS0c	0.255	0.255
GP01	1.945	1.945
GP02	-0.62	-0.62
GP0c	0.486	0.486
NOD	0.846	0.846
NZO	0.433	0.433
PWK	1.654	1.654
H37Rv_KO_CtpC	-1.4	-1.4
H37Rv_KO_CtpD	1.373	1.373
H37Rv_KO_Rv1272	0.569	0.569
H37Rv_KO_SugABC	-0.574	-0.574
H37Rv_KO_MbtN	0.322	0.322
Trans05	0.797	0.797
macrophage_unactivated	0.095	0.095
IL1	-0.457	-0.457
Rapamycin	-1.022	-1.022
Tcell	0.068	0.068
GMCSF	1.645	1.645
IFNab	0.753	0.753
IFNg	0.393	0.393
IFNg_GMCSF1	-0.591	-0.591
Rv1432_day32	1.566	1.566
Rv1565c_day32	-1.164	-1.164
secA2_input	-6.0	-6.0
delta_Rv3594	0.107	0.107
delta_Rv3717	0.004	0.004
delta_Rv3811	0.467	0.467
delta_Rv0954	-0.372	-0.372
PonA1	-0.373	-0.373
EccD1_KO	-2.5	-2.5
EspI_KO	-0.793	-0.793
PE35_KO	-0.77	-0.77
PPE68_KO	-1.35	-1.35
glycerol2	1.117	1.117
lignocerate	0.751	0.751
oleate	1.198	1.198
phosphatidylcholine	0.43	0.43
acetate	1.621	1.621
glucAc	1.713	1.713
Rv0950ko	0.069	0.069
Rv1096ko	-0.814	-0.814
Rv3684ko	-0.118	-0.118
delta_otsA_trehalose	-0.86	-0.86