TnSeqCorr

• These are correlations of TnSeq responses across 82 experimental conditions.
• LFCs (log2-fold-changes) were computed for each gene in each condition relative to a relevant control condition (e.g. H37Rv grown on 7H9).
• The LFCs were normalized by dividing by the standard deviation for each condition. (so roughly, |LFC|>2 are the outliers, i.e. tails of the distribution)
• Note that essential genes often have LFCs around 0.
• Data for some genes is not available if they have less than 3 TA sites, or the dynamic range of LFCs is less than 2.0 across all conditions. (This is the case for many essential genes.)
• 'leverage' on each plot is a statistical score that indicates how much the regression is influenced by a few outlier points; the traditional threshold is indicated on the plots (3p/n, which is about 0.07 for this dataset), but in practice, cases with leverage > ~0.2 seem to be the least reliable (most misleading) correlation coefficients.

Top 10 genes with highest correlation to Rv2485c/lipQ:
none

Correlation of Rv2485c/lipQ with Rv2485c/lipQ

Normalized LFCs for Rv2485c/lipQ:
(description and provenance of datasets)

	Rv2485c/lipQ	Rv2485c/lipQ
Fe_supp_jason_reseq	0.219	0.219
low_pH_jason_reseq	-0.047	-0.047
NO_jason_reseq	-0.286	-0.286
B6_jason_reseq	0.651	0.651
MHCII_jason_reseq	0.605	0.605
Isoniazid02	0.601	0.601
Rifampicin4	0.439	0.439
Ethambutol3	0.261	0.261
Meropenem3	0.534	0.534
Vancomycin16	0.377	0.377
Rv2680_day32	0.395	0.395
H37Rv_KO_MarP	0.303	0.303
hypoxia_3wks	0.227	0.227
hypoxia_6wks	0.894	0.894
glycerol	0.436	0.436
cholesterol	0.372	0.372
AJ	0.58	0.58
Bibs02	0.595	0.595
Bibs02c	0.744	0.744
BL6	-0.153	-0.153
BL6a	0.542	0.542
BXD01	-0.347	-0.347
BXD010	-0.46	-0.46
BXD011	-0.368	-0.368
BXD03	-0.678	-0.678
BXD04	-0.146	-0.146
BXD05	0.057	0.057
BXD06	-0.222	-0.222
BXD07	-0.498	-0.498
BXD08	0.254	0.254
BXD09	-0.214	-0.214
CAST	0.514	0.514
CCcont	-0.318	-0.318
DS01	0.542	0.542
DS02	0.941	0.941
DS04	0.097	0.097
DS0c	0.629	0.629
GP01	-0.043	-0.043
GP02	0.959	0.959
GP0c	-0.354	-0.354
NOD	0.932	0.932
NZO	0.519	0.519
PWK	-0.009	-0.009
H37Rv_KO_CtpC	-0.738	-0.738
H37Rv_KO_CtpD	-0.542	-0.542
H37Rv_KO_Rv1272	0.569	0.569
H37Rv_KO_SugABC	0.414	0.414
H37Rv_KO_MbtN	0.026	0.026
Trans05	-0.342	-0.342
macrophage_unactivated	0.221	0.221
IL1	-0.3	-0.3
Rapamycin	0.018	0.018
Tcell	-0.196	-0.196
GMCSF	0.343	0.343
IFNab	-0.348	-0.348
IFNg	-0.053	-0.053
IFNg_GMCSF1	0.352	0.352
Rv1432_day32	0.103	0.103
Rv1565c_day32	0.43	0.43
secA2_input	0.199	0.199
delta_Rv3594	-0.057	-0.057
delta_Rv3717	-0.078	-0.078
delta_Rv3811	-0.159	-0.159
delta_Rv0954	0.062	0.062
PonA1	0.173	0.173
EccD1_KO	0.941	0.941
EspI_KO	0.405	0.405
PE35_KO	0.551	0.551
PPE68_KO	0.429	0.429
glycerol2	0.454	0.454
lignocerate	0.605	0.605
oleate	0.157	0.157
phosphatidylcholine	0.434	0.434
acetate	0.171	0.171
glucAc	0.286	0.286
Rv0950ko	-0.374	-0.374
Rv1096ko	-0.374	-0.374
Rv3684ko	-0.249	-0.249
delta_otsA_trehalose	0.63	0.63