TnSeqCorr

• These are correlations of TnSeq responses across 82 experimental conditions.
• LFCs (log2-fold-changes) were computed for each gene in each condition relative to a relevant control condition (e.g. H37Rv grown on 7H9).
• The LFCs were normalized by dividing by the standard deviation for each condition. (so roughly, |LFC|>2 are the outliers, i.e. tails of the distribution)
• Note that essential genes often have LFCs around 0.
• Data for some genes is not available if they have less than 3 TA sites, or the dynamic range of LFCs is less than 2.0 across all conditions. (This is the case for many essential genes.)
• 'leverage' on each plot is a statistical score that indicates how much the regression is influenced by a few outlier points; the traditional threshold is indicated on the plots (3p/n, which is about 0.07 for this dataset), but in practice, cases with leverage > ~0.2 seem to be the least reliable (most misleading) correlation coefficients.

Top 10 genes with highest correlation to Rv1801/PPE29:
none

Correlation of Rv1801/PPE29 with Rv1801/PPE29

Normalized LFCs for Rv1801/PPE29:
(description and provenance of datasets)

	Rv1801/PPE29	Rv1801/PPE29
Fe_supp_jason_reseq	-0.011	-0.011
low_pH_jason_reseq	-0.698	-0.698
NO_jason_reseq	-0.155	-0.155
B6_jason_reseq	0.657	0.657
MHCII_jason_reseq	0.393	0.393
Isoniazid02	0.035	0.035
Rifampicin4	-0.068	-0.068
Ethambutol3	0.283	0.283
Meropenem3	0.547	0.547
Vancomycin16	-0.154	-0.154
Rv2680_day32	-0.28	-0.28
H37Rv_KO_MarP	0.08	0.08
hypoxia_3wks	-0.076	-0.076
hypoxia_6wks	0.04	0.04
glycerol	0.23	0.23
cholesterol	-0.372	-0.372
AJ	-0.01	-0.01
Bibs02	0.303	0.303
Bibs02c	0.146	0.146
BL6	0.087	0.087
BL6a	0.039	0.039
BXD01	-0.22	-0.22
BXD010	-0.084	-0.084
BXD011	-0.128	-0.128
BXD03	-0.261	-0.261
BXD04	-0.357	-0.357
BXD05	0.322	0.322
BXD06	0.142	0.142
BXD07	0.054	0.054
BXD08	-0.128	-0.128
BXD09	-0.265	-0.265
CAST	-0.018	-0.018
CCcont	-0.08	-0.08
DS01	0.327	0.327
DS02	0.052	0.052
DS04	0.2	0.2
DS0c	-0.009	-0.009
GP01	0.223	0.223
GP02	1.189	1.189
GP0c	-0.171	-0.171
NOD	-0.158	-0.158
NZO	-0.04	-0.04
PWK	0.092	0.092
H37Rv_KO_CtpC	-0.171	-0.171
H37Rv_KO_CtpD	0.079	0.079
H37Rv_KO_Rv1272	0.166	0.166
H37Rv_KO_SugABC	-0.024	-0.024
H37Rv_KO_MbtN	-0.576	-0.576
Trans05	-0.037	-0.037
macrophage_unactivated	0.249	0.249
IL1	0.157	0.157
Rapamycin	-0.255	-0.255
Tcell	-0.016	-0.016
GMCSF	0.111	0.111
IFNab	-0.302	-0.302
IFNg	0.436	0.436
IFNg_GMCSF1	0.434	0.434
Rv1432_day32	0.051	0.051
Rv1565c_day32	-0.376	-0.376
secA2_input	-0.686	-0.686
delta_Rv3594	0.147	0.147
delta_Rv3717	-0.174	-0.174
delta_Rv3811	-0.162	-0.162
delta_Rv0954	-0.376	-0.376
PonA1	-0.554	-0.554
EccD1_KO	-0.092	-0.092
EspI_KO	0.077	0.077
PE35_KO	0.563	0.563
PPE68_KO	0.538	0.538
glycerol2	0.59	0.59
lignocerate	0.491	0.491
oleate	0.404	0.404
phosphatidylcholine	0.647	0.647
acetate	0.09	0.09
glucAc	0.04	0.04
Rv0950ko	0.018	0.018
Rv1096ko	-0.145	-0.145
Rv3684ko	-0.383	-0.383
delta_otsA_trehalose	-0.645	-0.645