TnSeqCorr

• These are correlations of TnSeq responses across 82 experimental conditions.
• LFCs (log2-fold-changes) were computed for each gene in each condition relative to a relevant control condition (e.g. H37Rv grown on 7H9).
• The LFCs were normalized by dividing by the standard deviation for each condition. (so roughly, |LFC|>2 are the outliers, i.e. tails of the distribution)
• Note that essential genes often have LFCs around 0.
• Data for some genes is not available if they have less than 3 TA sites, or the dynamic range of LFCs is less than 2.0 across all conditions. (This is the case for many essential genes.)
• 'leverage' on each plot is a statistical score that indicates how much the regression is influenced by a few outlier points; the traditional threshold is indicated on the plots (3p/n, which is about 0.07 for this dataset), but in practice, cases with leverage > ~0.2 seem to be the least reliable (most misleading) correlation coefficients.

Top 10 genes with highest correlation to Rv1393c/-:
none

Correlation of Rv1393c/- with Rv1393c/-

Normalized LFCs for Rv1393c/-:
(description and provenance of datasets)

	Rv1393c/-	Rv1393c/-
Fe_supp_jason_reseq	-0.363	-0.363
low_pH_jason_reseq	-0.054	-0.054
NO_jason_reseq	-0.278	-0.278
B6_jason_reseq	-0.441	-0.441
MHCII_jason_reseq	0.038	0.038
Isoniazid02	-0.489	-0.489
Rifampicin4	0.225	0.225
Ethambutol3	0.136	0.136
Meropenem3	-0.186	-0.186
Vancomycin16	0.0	0.0
Rv2680_day32	-0.455	-0.455
H37Rv_KO_MarP	0.151	0.151
hypoxia_3wks	0.032	0.032
hypoxia_6wks	0.017	0.017
glycerol	-0.022	-0.022
cholesterol	-0.216	-0.216
AJ	-0.079	-0.079
Bibs02	0.05	0.05
Bibs02c	-0.233	-0.233
BL6	-0.677	-0.677
BL6a	0.138	0.138
BXD01	-0.373	-0.373
BXD010	0.299	0.299
BXD011	0.028	0.028
BXD03	0.15	0.15
BXD04	-0.176	-0.176
BXD05	-0.061	-0.061
BXD06	0.188	0.188
BXD07	-0.063	-0.063
BXD08	0.127	0.127
BXD09	0.015	0.015
CAST	-0.065	-0.065
CCcont	-0.406	-0.406
DS01	0.065	0.065
DS02	-0.424	-0.424
DS04	0.291	0.291
DS0c	0.207	0.207
GP01	0.222	0.222
GP02	0.462	0.462
GP0c	0.131	0.131
NOD	-0.306	-0.306
NZO	-0.137	-0.137
PWK	-0.067	-0.067
H37Rv_KO_CtpC	0.557	0.557
H37Rv_KO_CtpD	0.153	0.153
H37Rv_KO_Rv1272	0.366	0.366
H37Rv_KO_SugABC	-0.098	-0.098
H37Rv_KO_MbtN	0.429	0.429
Trans05	0.189	0.189
macrophage_unactivated	0.227	0.227
IL1	-0.044	-0.044
Rapamycin	0.089	0.089
Tcell	-0.169	-0.169
GMCSF	-0.119	-0.119
IFNab	0.281	0.281
IFNg	0.339	0.339
IFNg_GMCSF1	0.27	0.27
Rv1432_day32	-0.012	-0.012
Rv1565c_day32	0.008	0.008
secA2_input	0.546	0.546
delta_Rv3594	0.275	0.275
delta_Rv3717	-0.308	-0.308
delta_Rv3811	-0.155	-0.155
delta_Rv0954	0.362	0.362
PonA1	-0.099	-0.099
EccD1_KO	0.253	0.253
EspI_KO	0.602	0.602
PE35_KO	0.639	0.639
PPE68_KO	0.675	0.675
glycerol2	0.084	0.084
lignocerate	-0.135	-0.135
oleate	0.225	0.225
phosphatidylcholine	-0.021	-0.021
acetate	-0.429	-0.429
glucAc	-0.325	-0.325
Rv0950ko	0.567	0.567
Rv1096ko	0.205	0.205
Rv3684ko	0.124	0.124
delta_otsA_trehalose	-0.04	-0.04