TnSeqCorr

• These are correlations of TnSeq responses across 82 experimental conditions.
• LFCs (log2-fold-changes) were computed for each gene in each condition relative to a relevant control condition (e.g. H37Rv grown on 7H9).
• The LFCs were normalized by dividing by the standard deviation for each condition. (so roughly, |LFC|>2 are the outliers, i.e. tails of the distribution)
• Note that essential genes often have LFCs around 0.
• Data for some genes is not available if they have less than 3 TA sites, or the dynamic range of LFCs is less than 2.0 across all conditions. (This is the case for many essential genes.)
• 'leverage' on each plot is a statistical score that indicates how much the regression is influenced by a few outlier points; the traditional threshold is indicated on the plots (3p/n, which is about 0.07 for this dataset), but in practice, cases with leverage > ~0.2 seem to be the least reliable (most misleading) correlation coefficients.

Top 10 genes with highest correlation to Rv1107c/xseB:
none

Correlation of Rv1107c/xseB with Rv1107c/xseB

Normalized LFCs for Rv1107c/xseB:
(description and provenance of datasets)

	Rv1107c/xseB	Rv1107c/xseB
Fe_supp_jason_reseq	0.54	0.54
low_pH_jason_reseq	-0.582	-0.582
NO_jason_reseq	-1.78	-1.78
B6_jason_reseq	2.205	2.205
MHCII_jason_reseq	-1.317	-1.317
Isoniazid02	-0.355	-0.355
Rifampicin4	-0.544	-0.544
Ethambutol3	-0.497	-0.497
Meropenem3	0.486	0.486
Vancomycin16	-0.337	-0.337
Rv2680_day32	-0.584	-0.584
H37Rv_KO_MarP	-0.034	-0.034
hypoxia_3wks	0.518	0.518
hypoxia_6wks	-0.66	-0.66
glycerol	-0.132	-0.132
cholesterol	1.081	1.081
AJ	2.225	2.225
Bibs02	0.898	0.898
Bibs02c	1.898	1.898
BL6	-0.178	-0.178
BL6a	1.597	1.597
BXD01	-0.903	-0.903
BXD010	-0.067	-0.067
BXD011	-0.075	-0.075
BXD03	0.279	0.279
BXD04	-1.244	-1.244
BXD05	0.326	0.326
BXD06	-1.177	-1.177
BXD07	-0.334	-0.334
BXD08	-0.797	-0.797
BXD09	-0.026	-0.026
CAST	1.29	1.29
CCcont	0.323	0.323
DS01	0.438	0.438
DS02	0.107	0.107
DS04	-2.191	-2.191
DS0c	-2.531	-2.531
GP01	1.056	1.056
GP02	0.041	0.041
GP0c	0.866	0.866
NOD	0.994	0.994
NZO	2.429	2.429
PWK	1.408	1.408
H37Rv_KO_CtpC	-0.291	-0.291
H37Rv_KO_CtpD	-0.326	-0.326
H37Rv_KO_Rv1272	0.239	0.239
H37Rv_KO_SugABC	-2.293	-2.293
H37Rv_KO_MbtN	-1.474	-1.474
Trans05	0.0	0.0
macrophage_unactivated	-2.38	-2.38
IL1	-1.735	-1.735
Rapamycin	-2.424	-2.424
Tcell	-1.476	-1.476
GMCSF	2.173	2.173
IFNab	-0.402	-0.402
IFNg	-0.612	-0.612
IFNg_GMCSF1	-0.418	-0.418
Rv1432_day32	-0.343	-0.343
Rv1565c_day32	-0.463	-0.463
secA2_input	0.412	0.412
delta_Rv3594	1.791	1.791
delta_Rv3717	0.783	0.783
delta_Rv3811	0.681	0.681
delta_Rv0954	0.897	0.897
PonA1	-0.372	-0.372
EccD1_KO	-0.756	-0.756
EspI_KO	-1.634	-1.634
PE35_KO	-0.07	-0.07
PPE68_KO	1.613	1.613
glycerol2	1.852	1.852
lignocerate	1.785	1.785
oleate	2.019	2.019
phosphatidylcholine	1.529	1.529
acetate	1.845	1.845
glucAc	2.461	2.461
Rv0950ko	1.469	1.469
Rv1096ko	-0.042	-0.042
Rv3684ko	1.428	1.428
delta_otsA_trehalose	2.138	2.138