TnSeqCorr

• These are correlations of TnSeq responses across 82 experimental conditions.
• LFCs (log2-fold-changes) were computed for each gene in each condition relative to a relevant control condition (e.g. H37Rv grown on 7H9).
• The LFCs were normalized by dividing by the standard deviation for each condition. (so roughly, |LFC|>2 are the outliers, i.e. tails of the distribution)
• Note that essential genes often have LFCs around 0.
• Data for some genes is not available if they have less than 3 TA sites, or the dynamic range of LFCs is less than 2.0 across all conditions. (This is the case for many essential genes.)
• 'leverage' on each plot is a statistical score that indicates how much the regression is influenced by a few outlier points; the traditional threshold is indicated on the plots (3p/n, which is about 0.07 for this dataset), but in practice, cases with leverage > ~0.2 seem to be the least reliable (most misleading) correlation coefficients.

Top 10 genes with highest correlation to Rv0807/-:
none

Correlation of Rv0807/- with Rv0807/-

Normalized LFCs for Rv0807/-:
(description and provenance of datasets)

	Rv0807/-	Rv0807/-
Fe_supp_jason_reseq	-0.218	-0.218
low_pH_jason_reseq	-0.231	-0.231
NO_jason_reseq	-0.362	-0.362
B6_jason_reseq	-0.153	-0.153
MHCII_jason_reseq	0.977	0.977
Isoniazid02	0.949	0.949
Rifampicin4	2.545	2.545
Ethambutol3	1.251	1.251
Meropenem3	0.168	0.168
Vancomycin16	1.255	1.255
Rv2680_day32	0.0	0.0
H37Rv_KO_MarP	0.299	0.299
hypoxia_3wks	-0.606	-0.606
hypoxia_6wks	-2.088	-2.088
glycerol	1.232	1.232
cholesterol	0.378	0.378
AJ	0.089	0.089
Bibs02	1.481	1.481
Bibs02c	-3.647	-3.647
BL6	-2.18	-2.18
BL6a	-3.452	-3.452
BXD01	-2.27	-2.27
BXD010	-2.232	-2.232
BXD011	-1.594	-1.594
BXD03	-2.357	-2.357
BXD04	-2.155	-2.155
BXD05	-2.089	-2.089
BXD06	-2.326	-2.326
BXD07	-2.413	-2.413
BXD08	-2.318	-2.318
BXD09	-2.449	-2.449
CAST	-1.37	-1.37
CCcont	-2.453	-2.453
DS01	0.18	0.18
DS02	-1.293	-1.293
DS04	0.252	0.252
DS0c	-0.638	-0.638
GP01	-1.721	-1.721
GP02	-1.45	-1.45
GP0c	-2.266	-2.266
NOD	2.55	2.55
NZO	-1.406	-1.406
PWK	-0.577	-0.577
H37Rv_KO_CtpC	0.678	0.678
H37Rv_KO_CtpD	-1.763	-1.763
H37Rv_KO_Rv1272	-0.839	-0.839
H37Rv_KO_SugABC	-1.177	-1.177
H37Rv_KO_MbtN	0.152	0.152
Trans05	0.612	0.612
macrophage_unactivated	-3.794	-3.794
IL1	-3.565	-3.565
Rapamycin	-3.689	-3.689
Tcell	-3.917	-3.917
GMCSF	-3.174	-3.174
IFNab	-3.634	-3.634
IFNg	-2.844	-2.844
IFNg_GMCSF1	-3.343	-3.343
Rv1432_day32	0.0	0.0
Rv1565c_day32	0.0	0.0
secA2_input	-2.934	-2.934
delta_Rv3594	0.0	0.0
delta_Rv3717	0.0	0.0
delta_Rv3811	1.966	1.966
delta_Rv0954	3.517	3.517
PonA1	0.0	0.0
EccD1_KO	3.348	3.348
EspI_KO	2.287	2.287
PE35_KO	1.811	1.811
PPE68_KO	0.342	0.342
glycerol2	0.0	0.0
lignocerate	0.0	0.0
oleate	0.0	0.0
phosphatidylcholine	0.0	0.0
acetate	0.0	0.0
glucAc	0.0	0.0
Rv0950ko	-4.158	-4.158
Rv1096ko	1.08	1.08
Rv3684ko	-0.062	-0.062
delta_otsA_trehalose	1.125	1.125