TnSeqCorr

• These are correlations of TnSeq responses across 82 experimental conditions.
• LFCs (log2-fold-changes) were computed for each gene in each condition relative to a relevant control condition (e.g. H37Rv grown on 7H9).
• The LFCs were normalized by dividing by the standard deviation for each condition. (so roughly, |LFC|>2 are the outliers, i.e. tails of the distribution)
• Note that essential genes often have LFCs around 0.
• Data for some genes is not available if they have less than 3 TA sites, or the dynamic range of LFCs is less than 2.0 across all conditions. (This is the case for many essential genes.)
• 'leverage' on each plot is a statistical score that indicates how much the regression is influenced by a few outlier points; the traditional threshold is indicated on the plots (3p/n, which is about 0.07 for this dataset), but in practice, cases with leverage > ~0.2 seem to be the least reliable (most misleading) correlation coefficients.

Top 10 genes with highest correlation to Rv0471c/-:
none

Correlation of Rv0471c/- with Rv0471c/-

Normalized LFCs for Rv0471c/-:
(description and provenance of datasets)

	Rv0471c/-	Rv0471c/-
Fe_supp_jason_reseq	-0.103	-0.103
low_pH_jason_reseq	-0.581	-0.581
NO_jason_reseq	-0.441	-0.441
B6_jason_reseq	-0.457	-0.457
MHCII_jason_reseq	-0.605	-0.605
Isoniazid02	-0.138	-0.138
Rifampicin4	0.138	0.138
Ethambutol3	0.22	0.22
Meropenem3	0.246	0.246
Vancomycin16	0.544	0.544
Rv2680_day32	-1.021	-1.021
H37Rv_KO_MarP	0.645	0.645
hypoxia_3wks	-0.136	-0.136
hypoxia_6wks	-0.62	-0.62
glycerol	-0.55	-0.55
cholesterol	-0.57	-0.57
AJ	-0.575	-0.575
Bibs02	-0.135	-0.135
Bibs02c	0.158	0.158
BL6	0.227	0.227
BL6a	0.0	0.0
BXD01	0.229	0.229
BXD010	0.421	0.421
BXD011	-0.506	-0.506
BXD03	0.135	0.135
BXD04	0.337	0.337
BXD05	0.677	0.677
BXD06	0.036	0.036
BXD07	0.43	0.43
BXD08	-0.257	-0.257
BXD09	0.207	0.207
CAST	-0.13	-0.13
CCcont	-0.304	-0.304
DS01	0.145	0.145
DS02	-0.216	-0.216
DS04	-0.135	-0.135
DS0c	0.019	0.019
GP01	0.228	0.228
GP02	0.509	0.509
GP0c	0.057	0.057
NOD	0.159	0.159
NZO	-0.899	-0.899
PWK	-0.071	-0.071
H37Rv_KO_CtpC	0.507	0.507
H37Rv_KO_CtpD	0.755	0.755
H37Rv_KO_Rv1272	-0.572	-0.572
H37Rv_KO_SugABC	-0.038	-0.038
H37Rv_KO_MbtN	-1.1	-1.1
Trans05	-0.363	-0.363
macrophage_unactivated	0.275	0.275
IL1	0.083	0.083
Rapamycin	0.313	0.313
Tcell	-0.378	-0.378
GMCSF	0.409	0.409
IFNab	0.094	0.094
IFNg	-0.502	-0.502
IFNg_GMCSF1	-0.129	-0.129
Rv1432_day32	-0.724	-0.724
Rv1565c_day32	-0.085	-0.085
secA2_input	0.661	0.661
delta_Rv3594	-0.234	-0.234
delta_Rv3717	-0.156	-0.156
delta_Rv3811	-0.387	-0.387
delta_Rv0954	0.771	0.771
PonA1	-0.332	-0.332
EccD1_KO	-0.053	-0.053
EspI_KO	-0.205	-0.205
PE35_KO	-0.128	-0.128
PPE68_KO	-0.65	-0.65
glycerol2	0.643	0.643
lignocerate	0.253	0.253
oleate	0.641	0.641
phosphatidylcholine	0.434	0.434
acetate	-0.298	-0.298
glucAc	-0.038	-0.038
Rv0950ko	0.6	0.6
Rv1096ko	0.232	0.232
Rv3684ko	-0.151	-0.151
delta_otsA_trehalose	-0.324	-0.324