from: Boshoff et al (2004). The transcriptional responses of Mycobacterium tuberculosis to inhibitors of metabolism. J Biol Chem.

Gene Expression Profile for Rv2699c/-

LFC	treatment	description	class of inhibitor
3.148	Amikacin	ug/mL Amikacin	translation
1.948	Cap	5-10ug/mL Capreomycin	translation
1.935	Rox	10-50 ug/mL Roxithromycin	translation
1.390	SM	2-5 ug/mL Streptomycin	translation
3.651	Tet	5-10 ug/mL Tetracycline	translation
0.186	Rif	0.2-5ug/mL Rifampicin	transcription
1.431	Rifp	0.1-0.5ug/mL Rifapentine	transcription
-1.337	Min_med__succinate_	Minimal medium with succinate as sole carbon source as compared to growth in 7H9/ADC/Tween/glycerol	starvation
-0.172	CCCP	10-50 uM Carbonyl cyanide 3-chlorophenylhydrazone	respiration
-0.200	CPZ	10-50 ug/mL Chlorpromazine	respiration
-1.102	Clofazimine	10-13 ug/mL Clofazimine	respiration
-0.778	Clotrimazole	10-24 ug/mL Clotrimazole (azole drug)	respiration
-0.936	DCCD	20-100 uM Dicyclohexylcarbodiimide	respiration
-1.468	DNP	"0.5-2.5 mM 2,4-Dinitrophenol"	respiration
-0.761	DTT	"1-2 mM 1,4-Dithio-DL-threitol"	respiration
-0.548	Econazole	10-24 ug/mL Econazole (azole drug)	respiration
-0.345	GSNO_CFZ	0.1 mM S-Nitrosoglutathione + 5 ug/mL Clofazimine	respiration
-0.113	GSNO_CPZ	0.1 mM S-Nitrosoglutathione + 20-25 ug/mL Chlorpromazine	respiration
-1.623	GSNO_KCN	0.1mM S-Nitrosoglutathione + 5ug/mL potassium cyanide	respiration
0.936	GSNO_menadione	0.1 mM S-Nitrosoglutathione + 6-10 ug/mL menadione	respiration
-2.472	KCN	5-20 ug/mL Potassium cyanide	respiration
-1.058	NaN3	0.2-2 mM Sodium azide	respiration
1.947	Nigericin	50 uM Nigericin	respiration
-0.125	TRC	10-150 ug/mL Triclosan	respiration
1.061	TRZ	10-25 ug/mL Thioridazine	respiration
-0.199	Valinomycin	0.5-10 uM Valinomycin	respiration
-0.097	ZnSO4	2 mM ZnSO4	respiration
1.730	menadione	6-10 ug/mL Menadione	respiration
-0.362	Ascididemin_Nat_prod	4-9 ug/mL Organic extract of Eudistoma amplum	ironLimitation
0.339	Deferoxamine	150-250 uM Deferoxamine mesylate	ironLimitation
-0.212	Dipyridyl	"100-200 uM 2,2'-Bipyridyl"	ironLimitation
-0.137	GSNO	0.02-0.1mM S-Nitrosoglutathione	dosRassociated
1.115	NRP_1	Non-replicating persistence stage 1	dosRassociated
0.123	Amp	0.2mg/mL Ampicillin	cellWall
0.015	Cephalexin	20-100 ug/mL Cephalexin	cellWall
0.765	Cerulenin	0.32-5 ug/mL Cerulenin	cellWall
-0.020	DIPED	5-100 ug/mL Diisopropylethylenediamine	cellWall
0.200	EMB	10-20 ug/mL Ethambutol	cellWall
0.561	Eta	12-40 ug/mL Ethionamide	cellWall
0.974	INH	0.2-0.4 ug/mL Isoniazid	cellWall
0.059	TLM	0.1-0.2 mg/mL Thiolactomycin	cellWall
-0.410	Palmitate	Minimal medium with palmitate as sole C-source as compared to minimal medium with glucose as sole Csource	carbonSource
-0.413	Succinate	Minimal medium with succinate as sole C-source as compared to minimal medium with glucose as sole Csource	carbonSource
-0.694	BZA	0.12 mg/mL Benzamide	aromaticAmides
-0.777	Nam	0.12 - 1.2 mg/mL Nicotinamide	aromaticAmides
-0.148	PZA	0.12-1.2 mg/mL Pyrazinamide	aromaticAmides
-0.119	H2O2	4 mM hydrogen peroxide	DNAdamaging
-0.349	Levo	10 ug/mL Levofloxacin	DNAdamaging
0.270	Mtm	0.1-0.2 ug/mL Mitomycin C	DNAdamaging
-1.110	Novobiocin	10 ug/mL Novobiocin	DNAdamaging
0.366	Oflox	5-10 ug/mL Ofloxacin	DNAdamaging
0.315	UV	UV-irradiation	DNAdamaging
3.548	ARP4	1-4 ug/mL Antitubercular compound ARP4	?
-0.306	Antimycin	12.5-50 ug/mL Antimycin A	?
-0.092	DTNB	"1-2 mM 5,5'-Dithiobis(2-nitrobenzoic acid)"	?
-0.815	PA_1	10-50 ug/mL Antitubercular compound PA-1	?
-0.503	PA_21	10-50 ug/mL Antitubercular compound PA-21	?
-1.987	PA824	0.2-2 ug/mL PA-824	?
-0.911	Procept_6776	20-30 ug/mL Antitubercular compound Procept 6776	?
-0.566	Procept_6778	5-40 ug/mL Antitubercular compound Procept 6778	?
-0.456	Verapamil	50 uM Verapamil	?
-0.211	mercaptoethanol	2 mM 2-Mercaptoethanol	?
0.170	methoxatin	10-20 ug/mL Methoxatin	?