LFC | treatment | description | class of inhibitor |
0.372 | Amikacin | ug/mL Amikacin | translation |
0.117 | Cap | 5-10ug/mL Capreomycin | translation |
-0.296 | Rox | 10-50 ug/mL Roxithromycin | translation |
0.286 | SM | 2-5 ug/mL Streptomycin | translation |
1.261 | Tet | 5-10 ug/mL Tetracycline | translation |
-0.106 | Rif | 0.2-5ug/mL Rifampicin | transcription |
0.515 | Rifp | 0.1-0.5ug/mL Rifapentine | transcription |
-1.455 | Min_med__succinate_ | Minimal medium with succinate as sole carbon source as compared to growth in 7H9/ADC/Tween/glycerol | starvation |
2.316 | CCCP | 10-50 uM Carbonyl cyanide 3-chlorophenylhydrazone | respiration |
0.591 | CPZ | 10-50 ug/mL Chlorpromazine | respiration |
-1.078 | Clofazimine | 10-13 ug/mL Clofazimine | respiration |
-0.901 | Clotrimazole | 10-24 ug/mL Clotrimazole (azole drug) | respiration |
-0.059 | DCCD | 20-100 uM Dicyclohexylcarbodiimide | respiration |
0.488 | DNP | "0.5-2.5 mM 2,4-Dinitrophenol" | respiration |
0.498 | DTT | "1-2 mM 1,4-Dithio-DL-threitol" | respiration |
-0.311 | Econazole | 10-24 ug/mL Econazole (azole drug) | respiration |
-1.315 | GSNO_CFZ | 0.1 mM S-Nitrosoglutathione + 5 ug/mL Clofazimine | respiration |
0.822 | GSNO_CPZ | 0.1 mM S-Nitrosoglutathione + 20-25 ug/mL Chlorpromazine | respiration |
-0.249 | GSNO_KCN | 0.1mM S-Nitrosoglutathione + 5ug/mL potassium cyanide | respiration |
-1.119 | GSNO_menadione | 0.1 mM S-Nitrosoglutathione + 6-10 ug/mL menadione | respiration |
-0.038 | KCN | 5-20 ug/mL Potassium cyanide | respiration |
-1.933 | NaN3 | 0.2-2 mM Sodium azide | respiration |
1.400 | Nigericin | 50 uM Nigericin | respiration |
1.213 | TRC | 10-150 ug/mL Triclosan | respiration |
0.891 | TRZ | 10-25 ug/mL Thioridazine | respiration |
-0.440 | Valinomycin | 0.5-10 uM Valinomycin | respiration |
0.000 | ZnSO4 | 2 mM ZnSO4 | respiration |
-0.793 | menadione | 6-10 ug/mL Menadione | respiration |
0.131 | Ascididemin_Nat_prod | 4-9 ug/mL Organic extract of Eudistoma amplum | ironLimitation |
-0.225 | Deferoxamine | 150-250 uM Deferoxamine mesylate | ironLimitation |
0.138 | Dipyridyl | "100-200 uM 2,2'-Bipyridyl" | ironLimitation |
-0.176 | GSNO | 0.02-0.1mM S-Nitrosoglutathione | dosRassociated |
1.305 | NRP_1 | Non-replicating persistence stage 1 | dosRassociated |
-0.615 | Amp | 0.2mg/mL Ampicillin | cellWall |
-0.276 | Cephalexin | 20-100 ug/mL Cephalexin | cellWall |
0.838 | Cerulenin | 0.32-5 ug/mL Cerulenin | cellWall |
-0.773 | DIPED | 5-100 ug/mL Diisopropylethylenediamine | cellWall |
-0.859 | EMB | 10-20 ug/mL Ethambutol | cellWall |
-0.930 | Eta | 12-40 ug/mL Ethionamide | cellWall |
-1.296 | INH | 0.2-0.4 ug/mL Isoniazid | cellWall |
-0.219 | TLM | 0.1-0.2 mg/mL Thiolactomycin | cellWall |
-0.045 | Palmitate | Minimal medium with palmitate as sole C-source as compared to minimal medium with glucose as sole Csource | carbonSource |
-1.174 | Succinate | Minimal medium with succinate as sole C-source as compared to minimal medium with glucose as sole Csource | carbonSource |
1.040 | BZA | 0.12 mg/mL Benzamide | aromaticAmides |
0.344 | Nam | 0.12 - 1.2 mg/mL Nicotinamide | aromaticAmides |
-0.186 | PZA | 0.12-1.2 mg/mL Pyrazinamide | aromaticAmides |
0.217 | H2O2 | 4 mM hydrogen peroxide | DNAdamaging |
-0.249 | Levo | 10 ug/mL Levofloxacin | DNAdamaging |
-0.411 | Mtm | 0.1-0.2 ug/mL Mitomycin C | DNAdamaging |
0.468 | Novobiocin | 10 ug/mL Novobiocin | DNAdamaging |
-0.287 | Oflox | 5-10 ug/mL Ofloxacin | DNAdamaging |
-0.217 | UV | UV-irradiation | DNAdamaging |
1.121 | ARP4 | 1-4 ug/mL Antitubercular compound ARP4 | ? |
-0.462 | Antimycin | 12.5-50 ug/mL Antimycin A | ? |
-0.444 | DTNB | "1-2 mM 5,5'-Dithiobis(2-nitrobenzoic acid)" | ? |
-0.008 | PA_1 | 10-50 ug/mL Antitubercular compound PA-1 | ? |
0.209 | PA_21 | 10-50 ug/mL Antitubercular compound PA-21 | ? |
0.111 | PA824 | 0.2-2 ug/mL PA-824 | ? |
-0.238 | Procept_6776 | 20-30 ug/mL Antitubercular compound Procept 6776 | ? |
0.104 | Procept_6778 | 5-40 ug/mL Antitubercular compound Procept 6778 | ? |
-0.013 | Verapamil | 50 uM Verapamil | ? |
-0.482 | mercaptoethanol | 2 mM 2-Mercaptoethanol | ? |
0.303 | methoxatin | 10-20 ug/mL Methoxatin | ? |