LFC | treatment | description | class of inhibitor |
0.386 | Amikacin | ug/mL Amikacin | translation |
1.083 | Cap | 5-10ug/mL Capreomycin | translation |
2.592 | Rox | 10-50 ug/mL Roxithromycin | translation |
0.400 | SM | 2-5 ug/mL Streptomycin | translation |
1.055 | Tet | 5-10 ug/mL Tetracycline | translation |
0.492 | Rif | 0.2-5ug/mL Rifampicin | transcription |
0.639 | Rifp | 0.1-0.5ug/mL Rifapentine | transcription |
1.512 | Min_med__succinate_ | Minimal medium with succinate as sole carbon source as compared to growth in 7H9/ADC/Tween/glycerol | starvation |
-0.978 | CCCP | 10-50 uM Carbonyl cyanide 3-chlorophenylhydrazone | respiration |
-1.425 | CPZ | 10-50 ug/mL Chlorpromazine | respiration |
-1.800 | Clofazimine | 10-13 ug/mL Clofazimine | respiration |
0.215 | Clotrimazole | 10-24 ug/mL Clotrimazole (azole drug) | respiration |
-0.314 | DCCD | 20-100 uM Dicyclohexylcarbodiimide | respiration |
-1.508 | DNP | "0.5-2.5 mM 2,4-Dinitrophenol" | respiration |
-1.144 | DTT | "1-2 mM 1,4-Dithio-DL-threitol" | respiration |
-0.315 | Econazole | 10-24 ug/mL Econazole (azole drug) | respiration |
-1.875 | GSNO_CFZ | 0.1 mM S-Nitrosoglutathione + 5 ug/mL Clofazimine | respiration |
-1.354 | GSNO_CPZ | 0.1 mM S-Nitrosoglutathione + 20-25 ug/mL Chlorpromazine | respiration |
-1.944 | GSNO_KCN | 0.1mM S-Nitrosoglutathione + 5ug/mL potassium cyanide | respiration |
-1.274 | GSNO_menadione | 0.1 mM S-Nitrosoglutathione + 6-10 ug/mL menadione | respiration |
-1.537 | KCN | 5-20 ug/mL Potassium cyanide | respiration |
-0.629 | NaN3 | 0.2-2 mM Sodium azide | respiration |
0.268 | Nigericin | 50 uM Nigericin | respiration |
0.231 | TRC | 10-150 ug/mL Triclosan | respiration |
-0.587 | TRZ | 10-25 ug/mL Thioridazine | respiration |
0.187 | Valinomycin | 0.5-10 uM Valinomycin | respiration |
0.294 | ZnSO4 | 2 mM ZnSO4 | respiration |
-1.277 | menadione | 6-10 ug/mL Menadione | respiration |
-0.618 | Ascididemin_Nat_prod | 4-9 ug/mL Organic extract of Eudistoma amplum | ironLimitation |
0.448 | Deferoxamine | 150-250 uM Deferoxamine mesylate | ironLimitation |
-0.103 | Dipyridyl | "100-200 uM 2,2'-Bipyridyl" | ironLimitation |
0.004 | GSNO | 0.02-0.1mM S-Nitrosoglutathione | dosRassociated |
-1.253 | NRP_1 | Non-replicating persistence stage 1 | dosRassociated |
0.046 | Amp | 0.2mg/mL Ampicillin | cellWall |
0.115 | Cephalexin | 20-100 ug/mL Cephalexin | cellWall |
0.643 | Cerulenin | 0.32-5 ug/mL Cerulenin | cellWall |
0.250 | DIPED | 5-100 ug/mL Diisopropylethylenediamine | cellWall |
0.544 | EMB | 10-20 ug/mL Ethambutol | cellWall |
0.228 | Eta | 12-40 ug/mL Ethionamide | cellWall |
0.741 | INH | 0.2-0.4 ug/mL Isoniazid | cellWall |
0.212 | TLM | 0.1-0.2 mg/mL Thiolactomycin | cellWall |
-0.523 | Palmitate | Minimal medium with palmitate as sole C-source as compared to minimal medium with glucose as sole Csource | carbonSource |
-0.335 | Succinate | Minimal medium with succinate as sole C-source as compared to minimal medium with glucose as sole Csource | carbonSource |
0.366 | BZA | 0.12 mg/mL Benzamide | aromaticAmides |
0.603 | Nam | 0.12 - 1.2 mg/mL Nicotinamide | aromaticAmides |
0.548 | PZA | 0.12-1.2 mg/mL Pyrazinamide | aromaticAmides |
0.550 | H2O2 | 4 mM hydrogen peroxide | DNAdamaging |
0.353 | Levo | 10 ug/mL Levofloxacin | DNAdamaging |
0.312 | Mtm | 0.1-0.2 ug/mL Mitomycin C | DNAdamaging |
-1.267 | Novobiocin | 10 ug/mL Novobiocin | DNAdamaging |
0.294 | Oflox | 5-10 ug/mL Ofloxacin | DNAdamaging |
0.643 | UV | UV-irradiation | DNAdamaging |
-1.555 | ARP4 | 1-4 ug/mL Antitubercular compound ARP4 | ? |
-0.067 | Antimycin | 12.5-50 ug/mL Antimycin A | ? |
-0.288 | DTNB | "1-2 mM 5,5'-Dithiobis(2-nitrobenzoic acid)" | ? |
-1.103 | PA_1 | 10-50 ug/mL Antitubercular compound PA-1 | ? |
-1.369 | PA_21 | 10-50 ug/mL Antitubercular compound PA-21 | ? |
-1.318 | PA824 | 0.2-2 ug/mL PA-824 | ? |
-0.805 | Procept_6776 | 20-30 ug/mL Antitubercular compound Procept 6776 | ? |
0.037 | Procept_6778 | 5-40 ug/mL Antitubercular compound Procept 6778 | ? |
0.112 | Verapamil | 50 uM Verapamil | ? |
-0.370 | mercaptoethanol | 2 mM 2-Mercaptoethanol | ? |
-0.529 | methoxatin | 10-20 ug/mL Methoxatin | ? |