Rv1643 (rplT)

Current annotations:
- TBCAP: (community-based annotations - see table at bottom of page)
- TBDB: 50S ribosomal protein L20
- REFSEQ: 50S ribosomal protein L20
- PATRIC: LSU ribosomal protein L20p
- TUBERCULIST: 50S ribosomal protein L20 RplT
- NCBI: 50S ribosomal protein L20 RplT
- updated information (H37Rv4):
  - gene name: rplT
  - function:
  - reference:
Type: Not Target
Start: 1853184
End: 1853573
Operon:

Trans-membrane region:
Role: II.A.1 - Ribosomal protein synthesis and modification
GO terms:
- GO:0030529 - not-found (Uniprot)
- GO:0022625 - cytosolic large ribosomal subunit (Uniprot)
- GO:0019843 - rRNA binding (Uniprot)
- GO:0006412 - translation (Uniprot)
- GO:0005886 - plasma membrane (Uniprot)
- GO:0005840 - ribosome (Uniprot)
- GO:0005622 - intracellular (Uniprot)
- GO:0003735 - structural constituent of ribosome (Uniprot)
- GO:0003723 - RNA binding (Uniprot)
- GO:0000027 - ribosomal large subunit assembly (Uniprot)
Reaction(s) (based on iSM810 metabolic model):
Gene Expression Profile (Transcriptional Responses to Drugs; Boshoff et al, 2004)
Gene Modules extracted from cluster analysis of 249 transcriptomic datasets using ICA
Orthologs among selected mycobacteria
Protein structure:
Search for Homologs in PDB

Top 10 Homologs in PDB (as of Nov 2020):

PDB	aa ident	species	PDB title
5V93	100%	Mycobacterium tuberculosis	Cryo-EM structure of the 70S ribosome from Mycobacterium tuberculosis bound with Capreomycin
5V7Q	100%	Mycobacterium tuberculosis	Cryo-EM structure of the large ribosomal subunit from Mycobacterium tuberculosis bound with a potent linezolid analog
6DZP	91%	Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)	Cryo-EM Structure of Mycobacterium smegmatis C(minus) 50S ribosomal subunit
5ZET	91%	Mycobacterium smegmatis str. MC2 155	M. smegmatis P/P state 50S ribosomal subunit
5ZEP	91%	Mycobacterium smegmatis str. MC2 155	M. smegmatis hibernating state 70S ribosome structure
5ZEB	91%	Mycobacterium smegmatis str. MC2 155	M. Smegmatis P/P state 70S ribosome structure
5XYM	91%	Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)	Large subunit of Mycobacterium smegmatis
5O61	91%	Mycobacterium smegmatis str. MC2 155	The complete structure of the Mycobacterium smegmatis 70S ribosome
5O60	91%	Mycobacterium smegmatis str. MC2 155	Structure of the 50S large ribosomal subunit from Mycobacterium smegmatis
6DZI	91%	Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)	Cryo-EM Structure of Mycobacterium smegmatis 70S C(minus) ribosome 70S-MPY complex

Links to additional information on rplT:
- TBDB (updated)
- Phyre2 structure prediction, model: final.casp.pdb (from Mao et al, 2013)
- UniProt
- AlphaFold model
- Vulnerability = -11.022 (from Jeremy Rock's lab)
- KEGG - nucleotide and amino acid sequences of gene
- Mycobrowser
- PATRIC
- BioCyc
- Systems Biology

Amino Acid Sequence

MARVKRAVNAHKKRRSILKASRGYRGQRSRLYRKAKEQQLHSLNYAYRDRRARKGEFRKLWIARINAAARLNDITYNRLIQGLKAAGVEVDRKNLADIAI
SDPAAFTALVDVARAALPEDVNAPSGEAA

(Nucleotide sequence available on KEGG)

Additional Information

ESSENTIALITY

MtbTnDB - interactive tool for exploring a database of published TnSeq datasets for Mtb

TnSeqCorr - genes with correlated TnSeq profiles across >100 conditions *new*

Classification	Condition	Strain	Method	Reference	Notes
Non-Essential	Sodium Oleate	H37RvMA	Gumbel	Subhalaxmi Nambi	Probability of Essentiality: 0.001900; 5 non-insertions in a row out of 8 sites
Essential	Lignoceric Acid	H37RvMA	Gumbel	Subhalaxmi Nambi	Probability of Essentiality: 0.999650; 8 non-insertions in a row out of 8 sites
Essential	Phosphatidylcholine	H37RvMA	Gumbel	Subhalaxmi Nambi	Probability of Essentiality: 0.999950; 8 non-insertions in a row out of 8 sites
Essential	minimal media + 0.1% glycerol	H37RvMA	Gumbel	Griffin et al. (2011)	Probability of Essentiality: 0.999500; 8 non-insertions in a row out of 8 sites
Essential	minimal media + 0.01% cholesterol	H37RvMA	Gumbel	Griffin et al. (2011)	Probability of Essentiality: 0.999550; 8 non-insertions in a row out of 8 sites
No-Data	7H10-glycerol	H37RvMA	TraSH	Sassetti et al. (2003a)
Too-Short	C57BL/6J mice (8 weeks)	H37RvMA	TraSH	Sassetti et al. (2003b)	Hybridization Ratio: -1
Essential	7H09/7H10 + rich media	H37RvMA	MotifHMM	DeJesus et al. (2017)	Fully saturated (14 reps).

TnSeq Data No data currently available.

No TnSeq data currently available for this Target.

RNASeq Data No data currently available.

No RNA-Seq data currently available for this Target.

Metabolomic Profiles No data currently available.

No Metabolomic data currently available for this Target.

Proteomic Data No data currently available.

No Proteomic data currently available for this Target.

Regulatory Relationships from Systems Biology

BioCyc

Gene interactions based on ChIPSeq and Transcription Factor Over-Expression (TFOE) (Systems Biology)

NOTE: Green edges represent the connected genes being classified as differentially essential as a result of the middle gene being knocked out. These interactions are inferred based on RNASeq.

Interactions based on ChIPSeq data

RNA processing and modification

Energy production and conversion

Chromatin structure and dynamics

Amino acid transport and metabolism

Cell cycle control, cell division, chromosome partitioning

Carbohydrate transport and metabolism

Nucleotide transport and metabolism

Lipid transport and metabolism

Coenzyme transport and metabolism

Transcription

Translation, ribosomal structure and biogenesis

Cell wall/membrane/envelope biogenesis

Replication, recombination and repair

Posttranslational modification, protein turnover, chaperones

Cell motility

Secondary metabolites biosynthesis, transport and catabolism

Inorganic ion transport and metabolism

Function unknown

General function prediction only

Intracellular trafficking, secretion, and vesicular transport

Signal transduction mechanisms

Extracellular structures

Defense mechanisms

Nuclear structure

Cytoskeleton

BioCyc Co-regulated genes based on gene expression profiling (Systems Biology, Inferelator Network)

Differentially expressed as result of RNASeq in glycerol environment (Only top 20 genes shown sorted by log fold change with p_adj 0.05).

Conditionally essential as result of TNSeq (Only top 20 genes shown sorted by log fold change with p_adj 0.05).

BioCyc Transcription factor binding based on ChIP-Seq (Systems Biology)

Binds To:
- No bindings to other targets were found.
Bound By:
- No bindings from other targets were found.

Interactions based on ChIPSeq data (Minch et al. 2014)

Binds To:
- No bindings to other targets were found.
Bound By:
- No bindings to other targets were found.

Interactions based on TFOE data (Rustad et al. 2014)

Upregulates:
- Does not upregulate other genes.
Upregulated by:
- Not upregulated by other genes.
Downregulates:
- Does not downregulate other genes.
Downregulated by:
- Not downregulated by other genes.

TBCAP

Tubculosis Community Annotation Project (

Slayden et al., 2013

Rv1643 (rplT)

Property	Value	Creator	Evidence	PMID	Comment
Interaction	Transcription Rv1642	sourish10	ISO		Co-expression (Functional linkage) authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975
Interaction	Transcription Rv1643	sourish10	ISO		Co-expression (Functional linkage) authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975
Interaction	Transcription Rv1643	sourish10	ISO		Co-expression (Functional linkage) authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975
Interaction	Transcription Rv1642	sourish10	ISO		Co-expression (Functional linkage) authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975
Interaction	Transcription Rv1643	sourish10	ISO		Co-expression (Functional linkage) authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975
Interaction	Transcription Rv1643	sourish10	ISO		Co-expression (Functional linkage) authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975
Citation	Studies of oxygen binding energy to hemoglobin molecule. authors,YW. Chow,R. Pietranico,A. Mukerji Biochem. Biophys. Res. Commun. 1975	sourish10	ISO	6	Co-expression (Functional linkage)
Interaction	Transcription Rv1641	sourish10	ISO		Co-expression (Functional linkage) authors,YW. Chow,R. Pietranico,A. Mukerji Studies of oxygen binding energy to hemoglobin molecule. Biochem. Biophys. Res. Commun. 1975
Interaction	Transcription Rv1642	sourish10	ISO		Co-expression (Functional linkage) authors,YW. Chow,R. Pietranico,A. Mukerji Studies of oxygen binding energy to hemoglobin molecule. Biochem. Biophys. Res. Commun. 1975
Interaction	Transcription Rv1643	sourish10	ISO		Co-expression (Functional linkage) authors,YW. Chow,R. Pietranico,A. Mukerji Studies of oxygen binding energy to hemoglobin molecule. Biochem. Biophys. Res. Commun. 1975
Interaction	Transcription Rv1643	sourish10	ISO		Co-expression (Functional linkage) authors,YW. Chow,R. Pietranico,A. Mukerji Studies of oxygen binding energy to hemoglobin molecule. Biochem. Biophys. Res. Commun. 1975
Citation	Metal substitutions incarbonic anhydrase: a halide ion probe study. authors,RJ. Smith,RG. Bryant Biochem. Biophys. Res. Commun. 1975	sourish10	ISO	3	Co-expression (Functional linkage)
Interaction	Transcription Rv1641	sourish10	ISO		Co-expression (Functional linkage) authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975
Interaction	Transcription Rv1642	sourish10	ISO		Co-expression (Functional linkage) authors,F. Allemand,J. Haentjens,C. Chiaruttini,C. Royer,M. Springer Escherichia coli ribosomal protein L20 binds as a single monomer to its own mRNA bearing two potential binding sites. Nucleic Acids Res. 2007
Interaction	Transcription Rv1643	sourish10	ISO		Co-expression (Functional linkage) authors,F. Allemand,J. Haentjens,C. Chiaruttini,C. Royer,M. Springer Escherichia coli ribosomal protein L20 binds as a single monomer to its own mRNA bearing two potential binding sites. Nucleic Acids Res. 2007
Interaction	Transcription Rv1643	sourish10	ISO		Co-expression (Functional linkage) authors,F. Allemand,J. Haentjens,C. Chiaruttini,C. Royer,M. Springer Escherichia coli ribosomal protein L20 binds as a single monomer to its own mRNA bearing two potential binding sites. Nucleic Acids Res. 2007
Citation	Ribosomal protein L20 controls expression of the Bacillus subtilis infC operon via a transcription attenuation mechanism. authors,N. Choonee,S. Even,L. Zig,H. Putzer Nucleic Acids Res. 2007	sourish10	ISO	17289755	Co-expression (Functional linkage)
Interaction	Transcription Rv1641	sourish10	ISO		Co-expression (Functional linkage) authors,N. Choonee,S. Even,L. Zig,H. Putzer Ribosomal protein L20 controls expression of the Bacillus subtilis infC operon via a transcription attenuation mechanism. Nucleic Acids Res. 2007
Interaction	Transcription Rv1642	sourish10	ISO		Co-expression (Functional linkage) authors,N. Choonee,S. Even,L. Zig,H. Putzer Ribosomal protein L20 controls expression of the Bacillus subtilis infC operon via a transcription attenuation mechanism. Nucleic Acids Res. 2007
Interaction	Transcription Rv1643	sourish10	ISO		Co-expression (Functional linkage) authors,N. Choonee,S. Even,L. Zig,H. Putzer Ribosomal protein L20 controls expression of the Bacillus subtilis infC operon via a transcription attenuation mechanism. Nucleic Acids Res. 2007
Interaction	Transcription Rv1643	sourish10	ISO		Co-expression (Functional linkage) authors,N. Choonee,S. Even,L. Zig,H. Putzer Ribosomal protein L20 controls expression of the Bacillus subtilis infC operon via a transcription attenuation mechanism. Nucleic Acids Res. 2007
Citation	Metal substitutions incarbonic anhydrase: a halide ion probe study. authors,RJ. Smith,RG. Bryant Biochem. Biophys. Res. Commun. 1975	sourish10	ISO	3	Co-expression (Functional linkage)
Interaction	Transcription Rv1641	sourish10	ISO		Co-expression (Functional linkage) authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975
Interaction	Transcription Rv1641	sourish10	ISO		Affinity purification (Physical interaction) authors,YW. Chow,R. Pietranico,A. Mukerji Studies of oxygen binding energy to hemoglobin molecule. Biochem. Biophys. Res. Commun. 1975
Interaction	Transcription Rv1642	sourish10	ISO		Affinity purification (Physical interaction) authors,YW. Chow,R. Pietranico,A. Mukerji Studies of oxygen binding energy to hemoglobin molecule. Biochem. Biophys. Res. Commun. 1975
Interaction	Transcription Rv1643	sourish10	ISO		Affinity purification (Physical interaction) authors,YW. Chow,R. Pietranico,A. Mukerji Studies of oxygen binding energy to hemoglobin molecule. Biochem. Biophys. Res. Commun. 1975
Interaction	Transcription Rv1643	sourish10	ISO		Affinity purification (Physical interaction) authors,YW. Chow,R. Pietranico,A. Mukerji Studies of oxygen binding energy to hemoglobin molecule. Biochem. Biophys. Res. Commun. 1975
Citation	Metal substitutions incarbonic anhydrase: a halide ion probe study. authors,RJ. Smith,RG. Bryant Biochem. Biophys. Res. Commun. 1975	sourish10	ISO	3	Affinity purification (Physical interaction)
Interaction	Transcription Rv1641	sourish10	ISO		Affinity purification (Physical interaction) authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975
Interaction	Transcription Rv1642	sourish10	ISO		Affinity purification (Physical interaction) authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975
Interaction	Transcription Rv1643	sourish10	ISO		Affinity purification (Physical interaction) authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975
Interaction	Transcription Rv1643	sourish10	ISO		Affinity purification (Physical interaction) authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975
Citation	Escherichia coli ribosomal protein L20 binds as a single monomer to its own mRNA bearing two potential binding sites. authors,F. Allemand,J. Haentjens,C. Chiaruttini,C. Royer,M. Springer Nucleic Acids Res. 2007	sourish10	ISO	17439971	Co-expression (Functional linkage)
Interaction	Transcription Rv1641	sourish10	ISO		Co-expression (Functional linkage) authors,F. Allemand,J. Haentjens,C. Chiaruttini,C. Royer,M. Springer Escherichia coli ribosomal protein L20 binds as a single monomer to its own mRNA bearing two potential binding sites. Nucleic Acids Res. 2007
Interaction	Transcription Rv1641	sourish10	ISO		Affinity purification (Physical interaction) authors,N. Choonee,S. Even,L. Zig,H. Putzer Ribosomal protein L20 controls expression of the Bacillus subtilis infC operon via a transcription attenuation mechanism. Nucleic Acids Res. 2007
Interaction	Transcription Rv1642	sourish10	ISO		Affinity purification (Physical interaction) authors,N. Choonee,S. Even,L. Zig,H. Putzer Ribosomal protein L20 controls expression of the Bacillus subtilis infC operon via a transcription attenuation mechanism. Nucleic Acids Res. 2007
Interaction	Transcription Rv1643	sourish10	ISO		Affinity purification (Physical interaction) authors,N. Choonee,S. Even,L. Zig,H. Putzer Ribosomal protein L20 controls expression of the Bacillus subtilis infC operon via a transcription attenuation mechanism. Nucleic Acids Res. 2007
Interaction	Transcription Rv1643	sourish10	ISO		Affinity purification (Physical interaction) authors,N. Choonee,S. Even,L. Zig,H. Putzer Ribosomal protein L20 controls expression of the Bacillus subtilis infC operon via a transcription attenuation mechanism. Nucleic Acids Res. 2007
Citation	Metal substitutions incarbonic anhydrase: a halide ion probe study. authors,RJ. Smith,RG. Bryant Biochem. Biophys. Res. Commun. 1975	sourish10	ISO	3	Affinity purification (Physical interaction)
Interaction	Transcription Rv1641	sourish10	ISO		Affinity purification (Physical interaction) authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975
Interaction	Transcription Rv1642	sourish10	ISO		Affinity purification (Physical interaction) authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975
Interaction	Transcription Rv1643	sourish10	ISO		Affinity purification (Physical interaction) authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975
Interaction	Transcription Rv1643	sourish10	ISO		Affinity purification (Physical interaction) authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975
Citation	Studies of oxygen binding energy to hemoglobin molecule. authors,YW. Chow,R. Pietranico,A. Mukerji Biochem. Biophys. Res. Commun. 1975	sourish10	ISO	6	Affinity purification (Physical interaction)
Interaction	Transcription Rv1642	sourish10	ISO		Co-expression (Functional linkage) authors,YW. Chow,R. Pietranico,A. Mukerji Studies of oxygen binding energy to hemoglobin molecule. Biochem. Biophys. Res. Commun. 1975
Interaction	Transcription Rv1642	sourish10	ISO		Co-expression (Functional linkage) authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975
Citation	Escherichia coli ribosomal protein L20 binds as a single monomer to its own mRNA bearing two potential binding sites. authors,F. Allemand,J. Haentjens,C. Chiaruttini,C. Royer,M. Springer Nucleic Acids Res. 2007	sourish10	ISO	17439971	Affinity purification (Physical interaction)
Interaction	Transcription Rv1641	sourish10	ISO		Affinity purification (Physical interaction) authors,F. Allemand,J. Haentjens,C. Chiaruttini,C. Royer,M. Springer Escherichia coli ribosomal protein L20 binds as a single monomer to its own mRNA bearing two potential binding sites. Nucleic Acids Res. 2007
Interaction	Transcription Rv1642	sourish10	ISO		Affinity purification (Physical interaction) authors,F. Allemand,J. Haentjens,C. Chiaruttini,C. Royer,M. Springer Escherichia coli ribosomal protein L20 binds as a single monomer to its own mRNA bearing two potential binding sites. Nucleic Acids Res. 2007
Interaction	Transcription Rv1643	sourish10	ISO		Affinity purification (Physical interaction) authors,F. Allemand,J. Haentjens,C. Chiaruttini,C. Royer,M. Springer Escherichia coli ribosomal protein L20 binds as a single monomer to its own mRNA bearing two potential binding sites. Nucleic Acids Res. 2007
Interaction	Transcription Rv1643	sourish10	ISO		Affinity purification (Physical interaction) authors,F. Allemand,J. Haentjens,C. Chiaruttini,C. Royer,M. Springer Escherichia coli ribosomal protein L20 binds as a single monomer to its own mRNA bearing two potential binding sites. Nucleic Acids Res. 2007
Citation	Ribosomal protein L20 controls expression of the Bacillus subtilis infC operon via a transcription attenuation mechanism. authors,N. Choonee,S. Even,L. Zig,H. Putzer Nucleic Acids Res. 2007	sourish10	ISO	17289755	Affinity purification (Physical interaction)
Interaction	Transcription Rv1642	sourish10	ISO		Affinity purification (Physical interaction) authors,YW. Chow,R. Pietranico,A. Mukerji Studies of oxygen binding energy to hemoglobin molecule. Biochem. Biophys. Res. Commun. 1975
Interaction	Transcription Rv1642	sourish10	ISO		Affinity purification (Physical interaction) authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975
Interaction	Transcription Rv1642	sourish10	ISO		Co-expression (Functional linkage) authors,F. Allemand,J. Haentjens,C. Chiaruttini,C. Royer,M. Springer Escherichia coli ribosomal protein L20 binds as a single monomer to its own mRNA bearing two potential binding sites. Nucleic Acids Res. 2007
Interaction	Transcription Rv1642	sourish10	ISO		Co-expression (Functional linkage) authors,N. Choonee,S. Even,L. Zig,H. Putzer Ribosomal protein L20 controls expression of the Bacillus subtilis infC operon via a transcription attenuation mechanism. Nucleic Acids Res. 2007
Interaction	Transcription Rv1642	sourish10	ISO		Co-expression (Functional linkage) authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975
Interaction	Transcription Rv1642	sourish10	ISO		Affinity purification (Physical interaction) authors,F. Allemand,J. Haentjens,C. Chiaruttini,C. Royer,M. Springer Escherichia coli ribosomal protein L20 binds as a single monomer to its own mRNA bearing two potential binding sites. Nucleic Acids Res. 2007
Interaction	Transcription Rv1642	sourish10	ISO		Affinity purification (Physical interaction) authors,N. Choonee,S. Even,L. Zig,H. Putzer Ribosomal protein L20 controls expression of the Bacillus subtilis infC operon via a transcription attenuation mechanism. Nucleic Acids Res. 2007
Interaction	Transcription Rv1642	sourish10	ISO		Affinity purification (Physical interaction) authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975
Interaction	RegulatedBy Rv0348	yamir.moreno	IEP		Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. B. Abomoelak, EA. Hoye et al. mosR, a novel transcriptional regulator of hypoxia and virulence in Mycobacterium tuberculosis. J. Bacteriol. 2009

Property

Value

Creator

Evidence

PMID

Comment

Interaction

Transcription Rv1642

sourish10

ISO

Co-expression (Functional linkage)
authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975

Interaction

Transcription Rv1643

sourish10

ISO

Co-expression (Functional linkage)
authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975

Interaction

Transcription Rv1643

sourish10

ISO

Co-expression (Functional linkage)
authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975

Interaction

Transcription Rv1642

sourish10

ISO

Co-expression (Functional linkage)
authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975

Interaction

Transcription Rv1643

sourish10

ISO

Co-expression (Functional linkage)
authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975

Interaction

Transcription Rv1643

sourish10

ISO

Co-expression (Functional linkage)
authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975

Citation

Studies of oxygen binding energy to hemoglobin molecule. authors,YW. Chow,R. Pietranico,A. Mukerji Biochem. Biophys. Res. Commun. 1975

sourish10

ISO

Co-expression (Functional linkage)

Interaction

Transcription Rv1641

sourish10

ISO

Co-expression (Functional linkage)
authors,YW. Chow,R. Pietranico,A. Mukerji Studies of oxygen binding energy to hemoglobin molecule. Biochem. Biophys. Res. Commun. 1975

Interaction

Transcription Rv1642

sourish10

ISO

Co-expression (Functional linkage)
authors,YW. Chow,R. Pietranico,A. Mukerji Studies of oxygen binding energy to hemoglobin molecule. Biochem. Biophys. Res. Commun. 1975

Interaction

Transcription Rv1643

sourish10

ISO

Co-expression (Functional linkage)
authors,YW. Chow,R. Pietranico,A. Mukerji Studies of oxygen binding energy to hemoglobin molecule. Biochem. Biophys. Res. Commun. 1975

Interaction

Transcription Rv1643

sourish10

ISO

Co-expression (Functional linkage)
authors,YW. Chow,R. Pietranico,A. Mukerji Studies of oxygen binding energy to hemoglobin molecule. Biochem. Biophys. Res. Commun. 1975

Citation

Metal substitutions incarbonic anhydrase: a halide ion probe study. authors,RJ. Smith,RG. Bryant Biochem. Biophys. Res. Commun. 1975

sourish10

ISO

Co-expression (Functional linkage)

Interaction

Transcription Rv1641

sourish10

ISO

Co-expression (Functional linkage)
authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975

Interaction

Transcription Rv1642

sourish10

ISO

Co-expression (Functional linkage)
authors,F. Allemand,J. Haentjens,C. Chiaruttini,C. Royer,M. Springer Escherichia coli ribosomal protein L20 binds as a single monomer to its own mRNA bearing two potential binding sites. Nucleic Acids Res. 2007

Interaction

Transcription Rv1643

sourish10

ISO

Interaction

Transcription Rv1643

sourish10

ISO

Citation

Ribosomal protein L20 controls expression of the Bacillus subtilis infC operon via a transcription attenuation mechanism. authors,N. Choonee,S. Even,L. Zig,H. Putzer Nucleic Acids Res. 2007

sourish10

ISO

17289755

Co-expression (Functional linkage)

Interaction

Transcription Rv1641

sourish10

ISO

Co-expression (Functional linkage)
authors,N. Choonee,S. Even,L. Zig,H. Putzer Ribosomal protein L20 controls expression of the Bacillus subtilis infC operon via a transcription attenuation mechanism. Nucleic Acids Res. 2007

Interaction

Transcription Rv1642

sourish10

ISO

Interaction

Transcription Rv1643

sourish10

ISO

Interaction

Transcription Rv1643

sourish10

ISO

Citation

Metal substitutions incarbonic anhydrase: a halide ion probe study. authors,RJ. Smith,RG. Bryant Biochem. Biophys. Res. Commun. 1975

sourish10

ISO

Co-expression (Functional linkage)

Interaction

Transcription Rv1641

sourish10

ISO

Co-expression (Functional linkage)
authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975

Interaction

Transcription Rv1641

sourish10

ISO

Affinity purification (Physical interaction)
authors,YW. Chow,R. Pietranico,A. Mukerji Studies of oxygen binding energy to hemoglobin molecule. Biochem. Biophys. Res. Commun. 1975

Interaction

Transcription Rv1642

sourish10

ISO

Affinity purification (Physical interaction)
authors,YW. Chow,R. Pietranico,A. Mukerji Studies of oxygen binding energy to hemoglobin molecule. Biochem. Biophys. Res. Commun. 1975

Interaction

Transcription Rv1643

sourish10

ISO

Affinity purification (Physical interaction)
authors,YW. Chow,R. Pietranico,A. Mukerji Studies of oxygen binding energy to hemoglobin molecule. Biochem. Biophys. Res. Commun. 1975

Interaction

Transcription Rv1643

sourish10

ISO

Affinity purification (Physical interaction)
authors,YW. Chow,R. Pietranico,A. Mukerji Studies of oxygen binding energy to hemoglobin molecule. Biochem. Biophys. Res. Commun. 1975

Citation

Metal substitutions incarbonic anhydrase: a halide ion probe study. authors,RJ. Smith,RG. Bryant Biochem. Biophys. Res. Commun. 1975

sourish10

ISO

Affinity purification (Physical interaction)

Interaction

Transcription Rv1641

sourish10

ISO

Affinity purification (Physical interaction)
authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975

Interaction

Transcription Rv1642

sourish10

ISO

Affinity purification (Physical interaction)
authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975

Interaction

Transcription Rv1643

sourish10

ISO

Affinity purification (Physical interaction)
authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975

Interaction

Transcription Rv1643

sourish10

ISO

Affinity purification (Physical interaction)
authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975

Citation

Escherichia coli ribosomal protein L20 binds as a single monomer to its own mRNA bearing two potential binding sites. authors,F. Allemand,J. Haentjens,C. Chiaruttini,C. Royer,M. Springer Nucleic Acids Res. 2007

sourish10

ISO

17439971

Co-expression (Functional linkage)

Interaction

Transcription Rv1641

sourish10

ISO

Interaction

Transcription Rv1641

sourish10

ISO

Affinity purification (Physical interaction)
authors,N. Choonee,S. Even,L. Zig,H. Putzer Ribosomal protein L20 controls expression of the Bacillus subtilis infC operon via a transcription attenuation mechanism. Nucleic Acids Res. 2007

Interaction

Transcription Rv1642

sourish10

ISO

Interaction

Transcription Rv1643

sourish10

ISO

Interaction

Transcription Rv1643

sourish10

ISO

Citation

Metal substitutions incarbonic anhydrase: a halide ion probe study. authors,RJ. Smith,RG. Bryant Biochem. Biophys. Res. Commun. 1975

sourish10

ISO

Affinity purification (Physical interaction)

Interaction

Transcription Rv1641

sourish10

ISO

Affinity purification (Physical interaction)
authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975

Interaction

Transcription Rv1642

sourish10

ISO

Affinity purification (Physical interaction)
authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975

Interaction

Transcription Rv1643

sourish10

ISO

Affinity purification (Physical interaction)
authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975

Interaction

Transcription Rv1643

sourish10

ISO

Affinity purification (Physical interaction)
authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975

Citation

Studies of oxygen binding energy to hemoglobin molecule. authors,YW. Chow,R. Pietranico,A. Mukerji Biochem. Biophys. Res. Commun. 1975

sourish10

ISO

Affinity purification (Physical interaction)

Interaction

Transcription Rv1642

sourish10

ISO

Co-expression (Functional linkage)
authors,YW. Chow,R. Pietranico,A. Mukerji Studies of oxygen binding energy to hemoglobin molecule. Biochem. Biophys. Res. Commun. 1975

Interaction

Transcription Rv1642

sourish10

ISO

Co-expression (Functional linkage)
authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975

Citation

sourish10

ISO

17439971

Affinity purification (Physical interaction)

Interaction

Transcription Rv1641

sourish10

ISO

Affinity purification (Physical interaction)
authors,F. Allemand,J. Haentjens,C. Chiaruttini,C. Royer,M. Springer Escherichia coli ribosomal protein L20 binds as a single monomer to its own mRNA bearing two potential binding sites. Nucleic Acids Res. 2007

Interaction

Transcription Rv1642

sourish10

ISO

Interaction

Transcription Rv1643

sourish10

ISO

Interaction

Transcription Rv1643

sourish10

ISO

Citation

Ribosomal protein L20 controls expression of the Bacillus subtilis infC operon via a transcription attenuation mechanism. authors,N. Choonee,S. Even,L. Zig,H. Putzer Nucleic Acids Res. 2007

sourish10

ISO

17289755

Affinity purification (Physical interaction)

Interaction

Transcription Rv1642

sourish10

ISO

Affinity purification (Physical interaction)
authors,YW. Chow,R. Pietranico,A. Mukerji Studies of oxygen binding energy to hemoglobin molecule. Biochem. Biophys. Res. Commun. 1975

Interaction

Transcription Rv1642

sourish10

ISO

Affinity purification (Physical interaction)
authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975

Interaction

Transcription Rv1642

sourish10

ISO

Interaction

Transcription Rv1642

sourish10

ISO

Interaction

Transcription Rv1642

sourish10

ISO

Co-expression (Functional linkage)
authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975

Interaction

Transcription Rv1642

sourish10

ISO

Interaction

Transcription Rv1642

sourish10

ISO

Interaction

Transcription Rv1642

sourish10

ISO

Affinity purification (Physical interaction)
authors,RJ. Smith,RG. Bryant Metal substitutions incarbonic anhydrase: a halide ion probe study. Biochem. Biophys. Res. Commun. 1975

Interaction

RegulatedBy Rv0348

yamir.moreno

IEP

Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments..
B. Abomoelak, EA. Hoye et al. mosR, a novel transcriptional regulator of hypoxia and virulence in Mycobacterium tuberculosis. J. Bacteriol. 2009

Comments