TnSeqCorr

• These are correlations of TnSeq responses across 82 experimental conditions.
• LFCs (log2-fold-changes) were computed for each gene in each condition relative to a relevant control condition (e.g. H37Rv grown on 7H9).
• The LFCs were normalized by dividing by the standard deviation for each condition. (so roughly, |LFC|>2 are the outliers, i.e. tails of the distribution)
• Note that essential genes often have LFCs around 0.
• Data for some genes is not available if they have less than 3 TA sites, or the dynamic range of LFCs is less than 2.0 across all conditions. (This is the case for many essential genes.)
• 'leverage' on each plot is a statistical score that indicates how much the regression is influenced by a few outlier points; the traditional threshold is indicated on the plots (3p/n, which is about 0.07 for this dataset), but in practice, cases with leverage > ~0.2 seem to be the least reliable (most misleading) correlation coefficients.

Top 10 genes with highest correlation to Rv0890c/-:
none

Correlation of Rv0890c/- with Rv0890c/-

Normalized LFCs for Rv0890c/-:
(description and provenance of datasets)

	Rv0890c/-	Rv0890c/-
Fe_supp_jason_reseq	-0.177	-0.177
low_pH_jason_reseq	-0.069	-0.069
NO_jason_reseq	0.018	0.018
B6_jason_reseq	0.353	0.353
MHCII_jason_reseq	-0.013	-0.013
Isoniazid02	0.064	0.064
Rifampicin4	-0.187	-0.187
Ethambutol3	0.036	0.036
Meropenem3	0.34	0.34
Vancomycin16	0.157	0.157
Rv2680_day32	0.725	0.725
H37Rv_KO_MarP	0.43	0.43
hypoxia_3wks	0.072	0.072
hypoxia_6wks	-0.382	-0.382
glycerol	0.199	0.199
cholesterol	0.207	0.207
AJ	0.373	0.373
Bibs02	0.208	0.208
Bibs02c	-0.035	-0.035
BL6	0.439	0.439
BL6a	0.202	0.202
BXD01	0.058	0.058
BXD010	0.219	0.219
BXD011	-0.016	-0.016
BXD03	0.246	0.246
BXD04	0.233	0.233
BXD05	0.343	0.343
BXD06	0.101	0.101
BXD07	0.208	0.208
BXD08	-0.044	-0.044
BXD09	-0.172	-0.172
CAST	0.235	0.235
CCcont	-0.018	-0.018
DS01	0.019	0.019
DS02	0.088	0.088
DS04	0.169	0.169
DS0c	0.009	0.009
GP01	0.086	0.086
GP02	0.007	0.007
GP0c	-0.094	-0.094
NOD	0.631	0.631
NZO	0.348	0.348
PWK	0.237	0.237
H37Rv_KO_CtpC	0.284	0.284
H37Rv_KO_CtpD	0.19	0.19
H37Rv_KO_Rv1272	-0.147	-0.147
H37Rv_KO_SugABC	0.173	0.173
H37Rv_KO_MbtN	0.013	0.013
Trans05	-0.248	-0.248
macrophage_unactivated	0.237	0.237
IL1	0.172	0.172
Rapamycin	0.037	0.037
Tcell	0.114	0.114
GMCSF	-0.063	-0.063
IFNab	-0.181	-0.181
IFNg	0.532	0.532
IFNg_GMCSF1	0.339	0.339
Rv1432_day32	0.452	0.452
Rv1565c_day32	0.137	0.137
secA2_input	0.43	0.43
delta_Rv3594	-0.246	-0.246
delta_Rv3717	-0.561	-0.561
delta_Rv3811	-0.284	-0.284
delta_Rv0954	0.009	0.009
PonA1	0.015	0.015
EccD1_KO	0.23	0.23
EspI_KO	0.22	0.22
PE35_KO	-0.26	-0.26
PPE68_KO	-0.163	-0.163
glycerol2	0.286	0.286
lignocerate	0.259	0.259
oleate	0.362	0.362
phosphatidylcholine	0.357	0.357
acetate	-0.249	-0.249
glucAc	-0.212	-0.212
Rv0950ko	0.175	0.175
Rv1096ko	0.078	0.078
Rv3684ko	-0.383	-0.383
delta_otsA_trehalose	0.211	0.211