TnSeqCorr

• These are correlations of TnSeq responses across 82 experimental conditions.
• LFCs (log2-fold-changes) were computed for each gene in each condition relative to a relevant control condition (e.g. H37Rv grown on 7H9).
• The LFCs were normalized by dividing by the standard deviation for each condition. (so roughly, |LFC|>2 are the outliers, i.e. tails of the distribution)
• Note that essential genes often have LFCs around 0.
• Data for some genes is not available if they have less than 3 TA sites, or the dynamic range of LFCs is less than 2.0 across all conditions. (This is the case for many essential genes.)
• 'leverage' on each plot is a statistical score that indicates how much the regression is influenced by a few outlier points; the traditional threshold is indicated on the plots (3p/n, which is about 0.07 for this dataset), but in practice, cases with leverage > ~0.2 seem to be the least reliable (most misleading) correlation coefficients.

Top 10 genes with highest correlation to Rv0500B/-:
Show top 50 genes. Show bottom 10 genes with LOWEST correlation. none

Correlation of Rv0500B/- with Rv0500B/-

Normalized LFCs for Rv0500B/-:
(description and provenance of datasets)

Comparison of LFCs between selected condtions.

condition	Rv0500B/-	Rv0500B/-
Fe_supp_jason_reseq	2.545	2.545
low_pH_jason_reseq	2.033	2.033
NO_jason_reseq	3.368	3.368
B6_jason_reseq	0.866	0.866
MHCII_jason_reseq	-2.351	-2.351
Isoniazid02	2.289	2.289
Rifampicin4	-1.08	-1.08
Ethambutol3	0.839	0.839
Meropenem3	3.183	3.183
Vancomycin16	0.18	0.18
Rv2680_day32	-1.711	-1.711
H37Rv_KO_MarP	2.122	2.122
hypoxia_3wks	0.0	0.0
hypoxia_6wks	-2.575	-2.575
glycerol	0.67	0.67
cholesterol	-1.0	-1.0
AJ	0.129	0.129
Bibs02	-4.22	-4.22
Bibs02c	-3.942	-3.942
BL6	-2.887	-2.887
BL6a	-3.472	-3.472
BXD01	-3.006	-3.006
BXD010	-2.245	-2.245
BXD011	-1.89	-1.89
BXD03	-3.121	-3.121
BXD04	-2.094	-2.094
BXD05	-1.817	-1.817
BXD06	-1.218	-1.218
BXD07	-2.267	-2.267
BXD08	-0.918	-0.918
BXD09	-3.243	-3.243
CAST	-4.184	-4.184
CCcont	-0.124	-0.124
DS01	-4.62	-4.62
DS02	-4.254	-4.254
DS04	-4.108	-4.108
DS0c	-2.102	-2.102
GP01	-2.279	-2.279
GP02	-1.92	-1.92
GP0c	-2.129	-2.129
NOD	-3.677	-3.677
NZO	-2.533	-2.533
PWK	-3.005	-3.005
H37Rv_KO_CtpC	-3.44	-3.44
H37Rv_KO_CtpD	-2.074	-2.074
H37Rv_KO_Rv1272	-2.389	-2.389
H37Rv_KO_SugABC	-1.518	-1.518
H37Rv_KO_MbtN	-1.579	-1.579
Trans05	0.169	0.169
macrophage_unactivated	0.871	0.871
IL1	-0.475	-0.475
Rapamycin	1.872	1.872
Tcell	0.241	0.241
GMCSF	0.195	0.195
IFNab	-1.333	-1.333
IFNg	-1.462	-1.462
IFNg_GMCSF1	-0.245	-0.245
Rv1432_day32	0.0	0.0
Rv1565c_day32	0.0	0.0
secA2_input	-0.321	-0.321
delta_Rv3594	3.212	3.212
delta_Rv3717	0.797	0.797
delta_Rv3811	2.043	2.043
delta_Rv0954	5.438	5.438
PonA1	-0.56	-0.56
EccD1_KO	-3.203	-3.203
EspI_KO	0.804	0.804
PE35_KO	0.125	0.125
PPE68_KO	-1.526	-1.526
glycerol2	-2.396	-2.396
lignocerate	-2.004	-2.004
oleate	-4.143	-4.143
phosphatidylcholine	-2.978	-2.978
acetate	0.811	0.811
glucAc	0.692	0.692
Rv0950ko	0.449	0.449
Rv1096ko	-1.402	-1.402
Rv3684ko	1.077	1.077
delta_otsA_trehalose	0.0	0.0